Brees remained suited up on New Orleans’ sideline while Winston was in the game. Brees had been limited in practice over the past two weeks with a right shoulder injury. He is questionable to return.
Brees stayed in the game after absorbing a big hit that led to a personal-foul penalty by San Francisco 49ers defensive tackle Kentavius Street with 8:20 remaining in the second quarter. However, backup Taysom Hill took the next two snaps at QB after that snap, and Brees went to the sideline for one play to throw and try to get loose.
Brees re-entered the game to pitch the ball to Alvin Kamara for a 2-yard touchdown. Then he played the next series, completing five passes on another touchdown drive.
Brees, 41, has missed only six games due to injury in his 20-year NFL career — five of them in 2019 because of a torn ligament in his thumb.